OPEN MATRIX OLIF
SURFACE BY DESIGN ®
- SPIRA®-O Open Matrix OLIF and its open matrix design contain multiple pathways throughout the implant for osseointegration.
- Arched design distributes load evenly across endplates with optimized surface contact. Each implant offers up to 40 points of endplate contact.
- 3D printed titanium with Surface by Design® Technology, encourages bone cell proliferation with roughened titanium surface. 1,2,3,4,5,6
- Surface by Design® Titanium roughened surface is designed to have an average pore diameter approximately 500μm - the ideal environment for bony ingrowth. 7,8,9,10
OBLIQUE LUMBAR INTERBODY FUSION PROCEDURE
INSTRUMENTS AND IMPLANTS PASS THROUGH THE MOST NATURAL CORRIDOR TO THE DISC SPACE11
DESIGNED SPECIFICALLY FOR THE OLIF APPROACH
PrecisionInserter location feature placed at the optimal angle for atraumatic insertion
SafetyNo toggling of instruments in situ - instruments designed for safe implant delivery under direct visualization
InnovationImplant design utilizes proprietary open architecture and surface technology
SPIRA®-O INSTRUMENTS DESIGNED FOR:
 Olivares-Navarrete, Rene, et al. “Rough titanium alloys regulate osteoblast production of angiogenic factors.” The Spine Journal 13.11 (2013): 1563-1570. ;
 Olivares-Navarrete, Rene, et al. “Osteoblasts exhibit a more differentiated phenotype and increased bone morphogenetic protein production on titanium alloy substrates than on poly-ether-ether-ketone.” The Spine Journal 12.3 (2012): 265-272. ;
 Deligianni, D. D., et al. “Effect of surface roughness of the titanium alloy Ti–6Al–4V on human bone marrow cell response and on protein adsorption.” Biomaterials 22.11 (2001): 1241-1251.
 Boyan, B. D., et al. “Titanium surface roughness alters responsiveness of MG63 osteoblast-like cells to 1a, 25-(OH) 2D3.” Journal of biomedical materials research 39.1 (1998): 77-85. ;
 Lincks, J., et al. “Response of MG63 osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition.” Biomaterials 19.23 (1998): 2219-2232. ;
 Martin, J. Y., et al. “Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast‐like cells (MG63).” Journal of biomedical materials research 29.3 (1995): 389-401. ;
 Bobyn, J. D., et al. “The optimum pore size for the fixation of porous-surfaced metal implants by the ingrowth of bone.” Clinical orthopaedics and related research 150 (1980): 263-270. ;
 Karageorgiou, Vassilis, and David Kaplan. “Porosity of 3D biomaterial scaffolds and osteogenesis.” Biomaterials 26.27 (2005): 5474-5491. ;
 Hulbert, S. F., S. J. Morrison, and J. J. Klawitter. “Tissue reaction to three ceramics of porous and non‐porous structures.” Journal of biomedical materials research 6.5 (1972): 347-374. ;  Flatley, T. J., K. L. Lynch, and Mark Benson. “Tissue response to implants of calcium phosphat ceramic in the rabbit spine.” Clinical orthopaedics and related research 179 (1983): 246-252.
 Flatley, T. J., K. L. Lynch, and Mark Benson. “Tissue response to implants of calcium phosphat ceramic in the rabbit spine.” Clinical orthopaedics and related research 179 (1983): 246-252.
 Gragnaniello, C., & Seex, K. (2016). Anterior to psoas (ATP) fusion of the lumbar spine: evolution of a technique facilitated by changes in equipment. Journal of Spine Surgery. 2(4). 256-265. OSS Press. doi: 10.21037/jss.2016.11.02.